Sex Difference With Implications for Atherogenesis Androgen Receptor Expression Is Greater in Macrophages From Male Than From Female
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چکیده
Jane A. McCrohon, Alison K. Death, Shirley Nakhla, Wendy Jessup, David J. Handelsman, Donors : A Sex Difference With Implications for Atherogenesis Androgen Receptor Expression Is Greater in Macrophages From Male Than From Female Print ISSN: 0009-7322. Online ISSN: 1524-4539 Copyright © 2000 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Circulation doi: 10.1161/01.CIR.101.3.224 2000;101:224-226 Circulation. http://circ.ahajournals.org/content/101/3/224 World Wide Web at: The online version of this article, along with updated information and services, is located on the
منابع مشابه
Androgen receptor expression is greater in macrophages from male than from female donors. A sex difference with implications for atherogenesis.
BACKGROUND Male sex is an independent risk factor for the extent and severity of atherosclerosis. The influence of androgens on foam cell formation, a key event in atherogenesis, has not yet been investigated. METHODS AND RESULTS Primary human monocytes were allowed to differentiate into macrophages. RNA was then extracted from healthy male-donor (n=8) and premenopausal female-donor (n=8) mac...
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